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SESN2 attenuates sevoflurane-induced cognitive impairment and...

AbstractLong-term use of sevoflurane, an inhalation anesthetic, could negatively impact cognitive function. Current studies have suggested that cognitive impairment induced by sevoflurane may be...

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LncRNA-mir3471-limd1 regulatory network plays critical roles in HIBD

AbstractThe purpose of this study was to identify the target genes of tcon_00044595, elucidate its activation site, and provide novel insights into the pathogenesis and treatment of neonatal...

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Endometrioid carcinomas with sex cord-like formations and hyalinization:...

AbstractEndometrioid carcinoma with sex cord-like formations and hyalinization of the uterine corpus, or corded and hyalinized endometrioid adenocarcinoma (CHEC), is a rare morphological variant of...

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Intratumoral and peritumoral CT radiomics in predicting prognosis in patients...

AbstractObjectiveTo evaluate the efficacy of the CT-based intratumoral, peritumoral, and combined radiomics signatures in predicting progression-free survival (PFS) of patients with chondrosarcoma...

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Overactivated contextual visual perception and response to a single dose of...

AbstractThe pathogenesis of overactivated visual perception in attention-deficit hyperactivity disorder (ADHD) remains unclear, which is interpreted as a cognitive compensation. The existing studies...

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Correction: Iguratimod attenuated fbrosis in systemic sclerosis via targeting...

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Retraction Note: A New Cluster-Based MOF for Selective Gas Sorption and...

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Colquhounia root tablet in the treatment of idiopathic membranous nephropathy...

AbstractPurposeIdiopathic membranous nephropathy (IMN) is the most frequent global cause of nephrotic syndrome in non-diabetic people. In clinical practice, An effective and mild treatment for IMN...

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Review: Sample Pretreatment and Detection Strategies for Aflatoxins in Foods

AbstractAflatoxins (AFs) have strong liver and kidney toxicity, teratogenic, and carcinogenic effects. They can easily contaminate foods such as grains and oilseeds, and can easily enter the human body...

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Diagnosis of tomato pests and diseases based on lightweight CNN model

AbstractTomato crop yield can be negatively impacted by various diseases and pests. The application of computer vision to diagnose tomato diseases and pests presents two significant challenges....

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Effect of liquid nitrogen jet impingement angle on machinability of titanium...

AbstractIn order to further research the effect of cryogenic cooling, the cooling capacity of LN2 jet was studied through the theoretical and experimental methods. Based on the boiling cooling...

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Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of...

AbstractBackgroundDynamin-related protein 1 (Drp1)-mediated mitochondrial fission plays important roles in the activation, proliferation, and migration of T cells.MethodsWe investigated the synergistic...

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SPOP point mutations regulate substrate preference and affect its function

AbstractThe adaptor SPOP recruits substrates to CUL3 E3 ligase for ubiquitination and degradation. Structurally, SPOP harbors a MATH domain for substrate recognition, and a BTB domain responsible for...

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Characterization of sucrose nonfermenting-1-related protein kinase 2 (SnRK2)...

AbstractBackgroundThe sucrose nonfermenting-1-related protein kinase 2 (SnRK2) plays a crucial role in responses to diverse biotic/abiotic stresses. Currently, there are reports on these genes in...

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Adipose triglyceride lipase suppresses noncanonical inflammasome by...

AbstractIntracellular recognition of lipopolysaccharide (LPS) by mouse caspase-11 or human caspase-4 is a vital event for the activation of the noncanonical inflammasome. Whether negative regulators...

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The antimicrobial effect and mechanism of the Artemisia argyi essential oil...

AbstractArtemisia argyi is a traditional Chinese herb with antibacterial, antifungal, and antitumor activities. The essential oil of Artemisia argyi was extracted using the steam distillation method in...

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NLRC3 attenuates osteoclastogenesis by limiting TNFα+ Th17 cell response in...

AbstractNOD-like receptor family CARD domain containing 3 (NLRC3) is the intracellular protein belonging to NLR (NOD-like receptor) family. NLRC3 can negatively regulate inflammatory signal...

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Bacillus cereus cereolysin O induces pyroptosis in an undecapeptide-dependent...

AbstractBacillus cereus is a clinically significant foodborne pathogen that causes severe gastrointestinal and non-gastrointestinal disease. Cereolysin O (CLO) is a putative virulence factor of B....

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Physics-informed interpretable machine learning method for DOC monitoring in...

AbstractOnline monitoring of depths of cut (DOC) is an essential way to avoid machining defects, such as over-cutting and machining chatter. Data-driven machine learning method has been widely used to...

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Contrastive sequential interaction network learning on co-evolving Riemannian...

AbstractThe sequential interaction network usually find itself in a variety of applications, e.g., recommender system. Herein, inferring future interaction is of fundamental importance, and previous...

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